Detalhe da pesquisa
1.
Single-cell eQTL models reveal dynamic T cell state dependence of disease loci.
Nature
; 606(7912): 120-128, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35545678
2.
Advances in genetics toward identifying pathogenic cell states of rheumatoid arthritis.
Immunol Rev
; 294(1): 188-204, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31782165
3.
Annotations capturing cell type-specific TF binding explain a large fraction of disease heritability.
Hum Mol Genet
; 29(7): 1057-1067, 2020 05 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31595288
4.
Benchmarker: An Unbiased, Association-Data-Driven Strategy to Evaluate Gene Prioritization Algorithms.
Am J Hum Genet
; 104(6): 1025-1039, 2019 06 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31056107
5.
IMPACT: Genomic Annotation of Cell-State-Specific Regulatory Elements Inferred from the Epigenome of Bound Transcription Factors.
Am J Hum Genet
; 104(5): 879-895, 2019 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31006511
6.
Genes with High Network Connectivity Are Enriched for Disease Heritability.
Am J Hum Genet
; 104(5): 896-913, 2019 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31051114
7.
Two-dimensional IR spectroscopy of the anti-HIV agent KP1212 reveals protonated and neutral tautomers that influence pH-dependent mutagenicity.
Proc Natl Acad Sci U S A
; 112(11): 3229-34, 2015 Mar 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-25733867
8.
Genes with High Network Connectivity Are Enriched for Disease Heritability.
Am J Hum Genet
; 105(6): 1302, 2019 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-31809749
9.
High-dimensional phenotyping to define the genetic basis of cellular morphology.
Nat Commun
; 15(1): 347, 2024 Jan 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38184653
10.
Modeling tissue co-regulation estimates tissue-specific contributions to disease.
Nat Genet
; 55(9): 1503-1511, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37580597
11.
Fine-mapping causal tissues and genes at disease-associated loci.
medRxiv
; 2023 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37961337
12.
Dynamic regulatory elements in single-cell multimodal data implicate key immune cell states enriched for autoimmune disease heritability.
Nat Genet
; 55(12): 2200-2210, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-38036783
13.
Genetics of skeletal proportions in two different populations.
bioRxiv
; 2023 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37292977
14.
Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis.
Nat Genet
; 54(11): 1640-1651, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-36333501
15.
Population-specific causal disease effect sizes in functionally important regions impacted by selection.
Nat Commun
; 12(1): 1098, 2021 02 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33597505
16.
Improving the trans-ancestry portability of polygenic risk scores by prioritizing variants in predicted cell-type-specific regulatory elements.
Nat Genet
; 52(12): 1346-1354, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33257898
17.
Allele-specific expression changes dynamically during T cell activation in HLA and other autoimmune loci.
Nat Genet
; 52(3): 247-253, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32066938
18.
Large-scale genome-wide association study in a Japanese population identifies novel susceptibility loci across different diseases.
Nat Genet
; 52(7): 669-679, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32514122
19.
Early progression to active tuberculosis is a highly heritable trait driven by 3q23 in Peruvians.
Nat Commun
; 10(1): 3765, 2019 08 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31434886
20.
The power paradox of detecting disease-associated and gene-expression-associated variants.
Nat Genet
; 55(11): 1782-1783, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37857936